Main Street Inn Hilton Head Island   2200 Main Street, Hilton Head Island, SC 29926 US Check In Check Out 14+ Nights   10+ Rooms Rooms 1 2 3 4 5 6 7 8 9 10+ Adults/Rm 1 2 3 4 5 Photos of Main Street Inn Hilton Head Island Hotel Info • Video • Map • Rates & Availability   Select check-in date Select check-out date Learn more about Hilton Head Island Hotels in our Hilton Head Island Hotels Guide. Main Street Inn Hilton Head Island, 2200 Main Street, Hilton Head Island, South Carolina SC 29926

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