Hampton Inn Orangeburg   3583 St Matthews Road, I-26, Exit 145, Orangeburg, SC 29118 US Check In Check Out 14+ Nights   10+ Rooms Rooms 1 2 3 4 5 6 7 8 9 10+ Adults/Rm 1 2 3 4 5 Photos of Hampton Inn Orangeburg Hotel Info • Video • Map • Rates & Availability   Select check-in date Select check-out date Learn more about Orangeburg Hotels in our Orangeburg Hotels Guide. Hampton Inn Orangeburg, 3583 St Matthews Road, I-26, Exit 145, Orangeburg, South Carolina SC 29118

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